Propolis and its therapeutic potential on wound healing

Abstract

Propolis is a resinous mixture collected by honey bees from tree buds or other plant sources. Propolis compounds have been the focus of many studies due to their anti-microbial, anti-cancer, and antiinflammatory effects. In addition, propolis is also recognized to have regenerative properties. It has been found to regulate a number of cellular and molecular processes such as wound repair and regeneration, hemostasis, inflammation, cell proliferation, and tissue remodeling. Many in vivo studies on wound models show that propolis has beneficial roles in wound healing. These beneficial roles have also been confirmed by clinical research studies. However, more research is needed on the dose, side effects, and clinical efficacy of propolis on wounds. In conclusion, research with different experimental models is promising as a potential therapeutic strategy in wound healing.