Non-coding RNAs and Their Use in Cancer Diagnosis and Treatment
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Keywords:
Cancer, Non-coding RNAs, MicroRNAs, Long Non-coding RNAsAbstract
Non-coding RNAs (ncRNAs) are non-protein-coding RNAs that are involved in important cellular processes as well as in the regulation of gene expression. In recent years, ncRNAs have been implicated in cancerization and have been found to be valuable biomarkers for cancer diagnosis and treatment. Therefore, understanding gene expression and other important cellular processes regulated by ncRNA networks can provide significant new insights into cancer biology and further lead to the development of new and effective therapeutic strategies. ncRNAs, especially microRNAs (miRNAs) and Long non-coding RNAs (lncRNAs), act as decoys to affect the binding of regulatory molecules to target genes. Therefore, these unique molecules can play a role in cancer by regulating genes involved in cell growth, apoptosis, and angiogenesis. In conclusion, ncRNAs hold great potential for cancer diagnosis and treatment. Further research into the specific functions and mechanisms of these molecules in cancer will lead to the development of more effective therapeutic and/or diagnostic approaches for cancer patients.
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