A Comparative Study of ResNet and SE-ResNet Architectures on Medical Image Datasets


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Authors

  • Feyza Gizem GÜLER Tarsus University
  • Sara ALTUN GÜVEN Tarsus University
  • İrem ERSÖZ KAYA Tarsus University

Keywords:

Medical Image Synthesis, Deep Learning, ResNet, Squeeze-and-Excitation

Abstract

In this study, we investigate the effectiveness of different deep learning architectures in the task
of medical image synthesis using convolutional neural networks. Our goal is to compare the performance
of standard ResNet architectures (ResNet-18 and ResNet-50) with their Squeeze-and-Excitation (SE)
enhanced counterparts (SE-ResNet-18 and SE-ResNet-50). The evaluation is conducted on three publicly
available medical datasets: CVC-ClinicDB (colorectal polyp images), Messidor2 (retinal images), and Pap
Smear (cervical cell images). For image synthesis, we employ these architectures as generative backbones
and assess the quality of the generated images using both pixel-level metrics Mean Squared Error (MSE)
and perceptual similarity metrics, namely Fréchet Inception Distance (FID) and Kernel Inception Distance
(KID). Experimental results demonstrate that SE-enhanced ResNet architectures outperform their vanilla
counterparts in generating more realistic and perceptually coherent images. Particularly, SE-ResNet-50
achieves the lowest FID and KID scores across all datasets, indicating superior generative quality. These
findings highlight the impact of channel-wise attention mechanisms in enhancing feature representation
and improving medical image synthesis tasks. Experimental results demonstrate that ResNet50 achieves
the best performance across multiple metrics, including LPIPS, FID, KID, and MSE, confirming its
superiority in both perceptual quality and pixel-level accuracy.

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Author Biographies

Feyza Gizem GÜLER, Tarsus University

Computer Engineering department, Mersin

Sara ALTUN GÜVEN, Tarsus University

Computer Engineering department, Mersin

İrem ERSÖZ KAYA, Tarsus University

Computer Engineering department, Mersin

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Published

2025-07-21

How to Cite

GÜLER, F. G., ALTUN GÜVEN, S., & ERSÖZ KAYA, İrem. (2025). A Comparative Study of ResNet and SE-ResNet Architectures on Medical Image Datasets. International Journal of Advanced Natural Sciences and Engineering Researches, 9(7), 247–254. Retrieved from https://as-proceeding.com/index.php/ijanser/article/view/2771

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