Synthesis and Optimisation of Cinnamomum Zeylancium Loaded PLGA Nanoparticles
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Keywords:Poly Lactic-co-Glycolic Acid (PLGA), Polymeric Nanoparticles, In-vitro studies, Cinnamon, Kinetic Release Study
The capacity of nanoscale drug delivery systems to condense a variability of healing agents has been established. By encapsulating these plant extracts, the solubility and stability of drugs is increased. Cinnamon is a possible medicine for several curable diseases, such as diabetes. Nanoencapsulation of Cinnamomum zeylanicum powder was carried out using the solvent evaporation method to improve its bioavailability as a medication. The effect from PVA (polyvinyl alcohol) and Pluronic F-68 on organic solvents and surface-active agents has been investigated. Various parameters such as sonication time, outcome of PLGA content, effect of drug content was studied for optimization of Cinnamon loaded PLGA nanoparticles.
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