Synthesis and Optimisation of Cinnamomum Zeylancium Loaded PLGA Nanoparticles


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Authors

  • Vinod Kumari Panipat Institute of Engineering and Technology

DOI:

https://doi.org/10.59287/ijanser.46

Keywords:

Poly Lactic-co-Glycolic Acid (PLGA), Polymeric Nanoparticles, In-vitro studies, Cinnamon, Kinetic Release Study

Abstract

The capacity of nanoscale drug delivery systems to condense a variability of healing agents has been established. By encapsulating these plant extracts, the solubility and stability of drugs is increased. Cinnamon is a possible medicine for several curable diseases, such as diabetes. Nanoencapsulation of Cinnamomum zeylanicum powder was carried out using the solvent evaporation method to improve its bioavailability as a medication. The effect from PVA (polyvinyl alcohol) and Pluronic F-68 on organic solvents and surface-active agents has been investigated.  Various parameters such as sonication time, outcome of PLGA content, effect of drug content was studied for optimization of Cinnamon loaded PLGA nanoparticles.

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Author Biography

Vinod Kumari, Panipat Institute of Engineering and Technology

Department of Chemistry, India

References

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M. Esfandyari-Manesh et al., “Study of antimicrobial activity of anethole and carvone loaded PLGA nanoparticles,” J. Pharm. Res., vol. 7, no. 4, pp. 290–295, 2013.

Bohrey, S., Chourasiya, V., & Pandey, A. (2016). Polymeric nanoparticles containing diazepam: preparation, optimization, characterization, in-vitro drug release and release kinetic study. Nano Convergence, 3(1), 1-7.

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Published

2017-12-31

How to Cite

Kumari, V. (2017). Synthesis and Optimisation of Cinnamomum Zeylancium Loaded PLGA Nanoparticles. International Journal of Advanced Natural Sciences and Engineering Researches, 1(1), 1–4. https://doi.org/10.59287/ijanser.46

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