Arthrospira platensis in Family Medicine
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Keywords:
Arthrospira Platensis, Spirulina, Family Medicine, Functional Foods, Preventive HealthcareAbstract
Arthrospira platensis (commonly known as Spirulina) has emerged as a prominent microalga
with significant therapeutic and nutritional potential. This review investigates the role and applications of
A. platensis within family medicine by exploring its nutrient composition, health benefits, clinical
evidence, and implications for preventive healthcare. A systematic review methodology was utilized,
drawing from databases including PubMed, ScienceDirect, and Scopus, with inclusion criteria
emphasizing peer-reviewed articles from the past ten years. The principal findings indicate substantial
antioxidant, anti-inflammatory, and immunomodulatory effects, highlighting the microalga's potential as
a supportive therapeutic agent in managing chronic diseases such as metabolic syndrome, cardiovascular
diseases, diabetes mellitus type 2, and inflammation-related disorders. Challenges related to
standardization, clinical validation, and regulatory considerations are identified as critical areas for future
research. Ultimately, integrating A. platensis into family medicine practice could enhance patient
centered care through preventive and complementary health strategies.
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References
A. Çelekli and Ö. E. Zariç, “Breathing life into Mars: Terraforming and the pivotal role of algae in atmospheric genesis,” Life Sci. Sp. Res., vol. 41, pp. 181–190, May 2024, doi: 10.1016/j.lssr.2024.03.001.
A. Çelekli and Ö. E. Zariç, “Plasma-Enhanced Microalgal Cultivation: A Sustainable Approach for Biofuel and Biomass Production,” in Emerging Applications of Plasma Science in Allied Technologies, A. Shahzad and M. He, Eds. IGI Global, 2024, p. 300.
A. Çelekli and Ö. E. Zariç, “Assessing the environmental impact of functional foods,” 6th Int. Eurasian Conf. Biol. Chem. Sci., p. 103, 2023.
Ö. E. Zariç, İ. Yeşildağ, S. Yaygır, and A. Çelekli, “Removal of Harmful Dyes Using Some Algae,” in 3rd International Congress on Plant Biology; Rize, Turkey, Dec. 2022, no. 1st Edition, p. 173. doi: 10.5281/zenodo.8190776.
A. Çelekli, I. Yeşildağ, and Ö. E. Zariç, “Green building future: Algal application technology,” J. Sustain. Constr. Mater. Technol., vol. 9, no. 2, pp. 199–210, Jun. 2024, doi: 10.47481/jscmt.1348260.
Ö. E. Zariç and A. Çelekli, “Biotechnological Potential of Algae in Sustainable Development,” in 3rd International Conference on Engineering, Natural and Social Sciences, 2024.
A. Çelekli, E. Şeren, and Ö. E. Zariç, “Food Waste as a Barrier to Achieving Sustainability,” 2024.
L. Tomaselli, “Morphology, ultrastructure and taxonomy of Arthrospira (Spirulina) maxima and Arthrospira (Spirulina) platensis,” in Spirulina Platensis Arthrospira, CRC Press, 1997, pp. 1–15.
G. Gentscheva et al., “Application of Arthrospira platensis for Medicinal Purposes and the Food Industry: A Review of the Literature,” Life, vol. 13, no. 3, p. 845, Mar. 2023, doi: 10.3390/life13030845.
R. Kumar, A. S. Hegde, K. Sharma, P. Parmar, and V. Srivatsan, “Microalgae as a sustainable source of edible proteins and bioactive peptides–Current trends and future prospects,” Food Res. Int., vol. 157, p. 111338, 2022.
B. Marjanović et al., “Bioactive Compounds from Spirulina spp.—Nutritional Value, Extraction, and Application in Food Industry,” Separations, vol. 11, no. 9, p. 257, 2024.
ActiveCells, “Spirulina – ActiveCells®,” 2025. https://www.activecells.ae/spirulina/ (accessed May 30, 2025).
K. Janda-Milczarek et al., “Spirulina supplements as a source of mineral nutrients in the daily diet,” Appl. Sci., vol. 13, no. 2, p. 1011, 2023.
R. Ansari, F. Foroughinia, A. H. Dadbakhsh, F. Afsari, and M. M. Zarshenas, “An overview of pharmacological and clinical aspects of Spirulina,” Curr. Drug Discov. Technol., vol. 20, no. 2, pp. 74–88, 2023.
S. Sahil, S. Bodh, and P. Verma, “Spirulina platensis: A comprehensive review of its nutritional value, antioxidant activity and functional food potential,” J. Cell. Biotechnol., vol. 10, no. 2, pp. 1–14, 2024, doi: 10.3233/jcb-240151.
S. Lordan, R. P. Ross, and C. Stanton, “Marine bioactives as functional food ingredients: potential to reduce the incidence of chronic diseases,” Mar. Drugs, vol. 9, no. 6, pp. 1056–1100, 2011.
M. R. O. B. da Silva et al., “Therapeutical Potential and Immunomodulatory Profile of Arthrospira platensis Compounds against Chagas Disease,” ACS Infect. Dis., vol. 11, no. 4, pp. 1008–1017, 2025.
E. Nouri, H. Abbasi, and E. Rahimi, “Effects of processing on stability of water-and fat-soluble vitamins, pigments (C-phycocyanin, carotenoids, chlorophylls) and colour characteristics of Spirulina platensis,” Qual. Assur. Saf. Crop. Foods, vol. 10, no. 4, pp. 335–349, 2018.
S. Moradi, R. Ziaei, S. Foshati, H. Mohammadi, S. M. Nachvak, and M. H. Rouhani, “Effects of Spirulina supplementation on obesity: A systematic review and meta-analysis of randomized clinical trials,” Complement. Ther. Med., vol. 47, p. 102211, 2019.
O. A. ElFar et al., “Advances in delivery methods of Arthrospira platensis (spirulina) for enhanced therapeutic outcomes,” Bioengineered, vol. 13, no. 6, pp. 14681–14718, 2022, doi: 10.1080/21655979.2022.2100863.
P. Han et al., “Anti-oxidation properties and therapeutic potentials of spirulina,” Algal Res., vol. 55, p. 102240, 2021.
P. D. Karkos, S. C. Leong, C. D. Karkos, N. Sivaji, and D. A. Assimakopoulos, “Spirulina in Clinical Practice: Evidence‐Based Human Applications,” Evidence-Based Complement. Altern. Med., vol. 2011, no. 1, Jan. 2011, doi: 10.1093/ecam/nen058.
Q. Liu, Y. Huang, R. Zhang, T. Cai, and Y. Cai, “Medical application of Spirulina platensis derived C‐phycocyanin,” Evidence‐Based Complement. Altern. Med., vol. 2016, no. 1, p. 7803846, 2016.
H. Gorjzdadeh, N. Sakhaei, B. Doustshenas, K. Ganemi, and B. Archangi, “Fatty acid composition of Spirulina sp., Chlorella sp. and Chaetoceros sp. microalgae and introduction as potential new sources to extinct omega 3 and omega 6,” Iran. South Med. J., vol. 19, no. 2, pp. 212–224, 2016.
G. Tang and P. M. Suter, “Vitamin A, nutrition, and health values of Algae: Spirulina, chlorella, and dunaliella,” J. Pharm. Nutr. Sci., vol. 1, no. 2, pp. 111–118, 2011, doi: 10.6000/1927-5951.2011.01.02.04.
L. M. Moreira, A. C. Ribeiro, F. A. Duarte, M. G. de Morais, and L. A. de S. Soares, “Spirulina platensis biomass cultivated in Southern Brazil as a source of essential minerals and other nutrients,” 2013.
M.-C. Serban et al., “A systematic review and meta-analysis of the impact of Spirulina supplementation on plasma lipid concentrations,” Clin. Nutr., vol. 35, no. 4, pp. 842–851, 2016.
A. Nazir, M. un Nisa, M. A. Rahim, I. A. Mohamed Ahmed, and M. O. Aljobair, “Spirulina Unleashed: A Pancreatic Symphony to Restore Glycemic Balance and Improve Hyperlipidemia and Antioxidant Properties by Transcriptional Modulation of Genes in a Rat Model,” Foods, vol. 13, no. 21, p. 3512, 2024.
V. Prete, A. C. Abate, P. Di Pietro, M. De Lucia, C. Vecchione, and A. Carrizzo, “Beneficial effects of spirulina supplementation in the management of cardiovascular diseases,” Nutrients, vol. 16, no. 5, p. 642, 2024.
E. Hatami et al., “The effect of spirulina on type 2 diabetes: a systematic review and meta-analysis,” J. Diabetes Metab. Disord., vol. 20, pp. 883–892, 2021.
